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Human papillomavirus (HPV) infection in humans can cause cutaneous lesions (verruca vulgaris, filiform warts, verruca plana, plantar warts, anogenital warts, and Bowenoid papulosis), mucosal lesions (oral warts, condylomata, focal epithelial hyperplasia or Heck disease, nasal/conjunctival papillomas, laryngeal papillomas), and cervical lesions. Humans can also acts as asymptomatic carriers of HPV.

This patient had extensive warts on hands and feet not responding to treatment. Immunodeficiency was suspected but ruled out after exhaustive investigation.

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