Image Description
Introduction: Fibrous hamartoma of infancy (FHI) is a rare benign fibrous tumor of childhood with a characteristic organoid, triphasic appearance consisting of intersecting fascicles of cytologically bland fibroblastic/myofibroblastic cells (pink areas in this image), vascular nodules of primitive mesenchymal tissue (left half of the image), and mature adipose tissue.
Clinical Features: More than 90% of cases occur in the 1st year of life (range - birth to 15 years; median age 10 months). About 20% of cases are congenital. It is more common in boys (M:F=3:1).
Sites: The most common location is axilla followed by shoulder, upper arm, back, thigh, genital area, chest and forearm. Hands and feet are rarely affected. It presents as a small, solitary, painless, rapidly growing mass that is freely mobile but may sometimes be fixed to the fascia. After initial rapid phase, the growth slows but the lesion does not regress spontaneously.
Clinical Features: More than 90% of cases occur in the 1st year of life (range - birth to 15 years; median age 10 months). About 20% of cases are congenital. It is more common in boys (M:F=3:1).
Sites: The most common location is axilla followed by shoulder, upper arm, back, thigh, genital area, chest and forearm. Hands and feet are rarely affected. It presents as a small, solitary, painless, rapidly growing mass that is freely mobile but may sometimes be fixed to the fascia. After initial rapid phase, the growth slows but the lesion does not regress spontaneously.