Adamantinomatous Craniopharyngioma

Craniopharyngioma is a WHO Grade 1 epithelial tumor usually seen in the sellar/suprasellar region. It arises most likely from the remnants of Rathke's pouch. Some cases may have their origin in misplaced odontogenic rests along pituitary stalk. Grossly, they are often solid and cystic with areas of calcification. The cystic areas are multilocular and filled with dark fluid rich in cholesterol which has been likened to "motor oil" in appearance. The image shows an irregularly shaped solid and cystic lesion which was confirmed to be adamantinomatous craniopharyngioma on microscopic examination.