Ovarian Carcinoid : Microscopic
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Microscopic Features: The morphology of primary ovarian carcinoids is similar to that seen in other locations. Five architectural patterns have been recognized: insular (50% of cases), strumal carcinoid (40% of cases), trabecular, mucinous, and mixed type. The tumor cells have abundant eosinophilic cytoplasm and may show red-brown argentaffin granules.
The nuclei are uniform and have salt and pepper chromatin. Mitotic activity is low. Well-differentiated mucinous glands are seen in about 40% of cases. Teratomatous elements may be found in the ipsilateral or the contralateral ovary. Some ovarian carcinoids are associated with Brenner tumor or mucinous cystadenoma.
The nuclei are uniform and have salt and pepper chromatin. Mitotic activity is low. Well-differentiated mucinous glands are seen in about 40% of cases. Teratomatous elements may be found in the ipsilateral or the contralateral ovary. Some ovarian carcinoids are associated with Brenner tumor or mucinous cystadenoma.