Intestinal Metaplasia
Section Editor: Dharam M. Ramnani, MD
Virginia Urology, Richmond, VA, USA
Image Description
Intestinal metaplasia with mucin extravasation. Note the complete lack of cytologic atypia within the glands. Increased mitotic activity and necrosis are also absent. In contrast, cases of well-differentiated adenocarcinoma will show overt malignant features at least focally. The extravasated mucin in well-differentiated adenocarcinomas also tends to involve muscularis propria more extensively.