Section Editor: Dharam M. Ramnani, MD

Virginia Urology, Richmond, VA, USA

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Macroscopic Features: Simple cortical cysts of the kidney may be solitary or multiple and unilateral or bilateral. They are exophytic, thin-walled, translucent, usually unilocular and filled with clear serous fluid. The median diameter is about 5 cm but they may reach enormous sizes. The inner wall is smooth or trabeculated and is lined by a single layer of flattened or low-cuboidal epithelium. Long-standing cysts may show a thick, calcified wall containing hemosiderin-laden macrophages, chronic inflammatory infiltrate and atrophic or no epithelial lining.

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