Renal Cell Carcinoma with Angiomyolipoma

The multinodular tumor in the upper half of the specimen is clear cell renal cell carcinoma. The nodules have variable appearance ranging from the classic yellow-gold appearance to brown, likely due to remote hemorrhage, while other parts of the tumor have cystic change with more recent bright red hemorrhage. Remote and acute hemorrhage are common in these vascular tumors. A nodule representing carcinoma is seen near the renal sinus. The tumor in the lower right of the specimen is an angiomyolipoma. Angiomyolipoma can be composed of varying proportions of the three components seen, namely: blood vessels, smooth muscle and adipose tissue. The homogeneous, yellow appearance indicates this specific tumor likely is composed mostly of adipose tissue. Image copyright: pathorama.ch