Juxtaglomerular Cell Tumor
Section Editor: Dharam M. Ramnani, MD
Virginia Urology, Richmond, VA, USA
Image Description
Juxtaglomerular cell tumor is highly vascular and consists of small venules, muscular arterioles, and capillaries interposed between monomorphic tumor cells. Branching vessels with "stag-horn" configuration resembling those seen in hemangiopericytoma may also be present. The tumor arises from juxtaglomerular cells - specialized smooth muscle cells in the afferent arteriole of the juxtaglomerular apparatus which plays a role in regulating blood pressure via renin release.