Primary Renal Lymphoma

Primary Renal Lymphoma: It is uncommon and accounts for <1% of all extranodal lymphomas. The involvement is limited to one or both kidneys. About 10-20% are bilateral. The patients are usually in their 5th-7th decades of life. Pediatric cases have been reported. The clinical presentation includes flank pain, hematuria, pyuria, fatigue, weight loss, fever, night sweats, abdominal mass, abdominal pain, and renal insufficiency (late stages of the disease). Some cases are discovered incidentally. This autopsy specimen photo shows diffuse involvement of the kidney by a pink-tan, ill-defined, infiltrative tumor. The patient succumbed to diffuse large B-cell lymphoma with multi-organ involvement.