Image Description
Squamous differentiation in gallbladder carcinomas can show one of many patterns. Approximately 5% of cases show focal squamous differentiation. Pure squamous cell carcinomas are exceedingly rare (<1% of all gallbladder carcinomas). The term adenosquamous carcinoma is applied when >25% of the tumor is composed of squamous elements.
Based on these criteria, the example shown here is an adenosquamous carcinoma. There are glandular elements on the left and well-differentiated squamous clusters with keratinization on the right. Some of the squamous clusters had lumen and an inner lining of glandular epithelium.
Based on these criteria, the example shown here is an adenosquamous carcinoma. There are glandular elements on the left and well-differentiated squamous clusters with keratinization on the right. Some of the squamous clusters had lumen and an inner lining of glandular epithelium.