Gallbladder Carcinoma : Histologic Grading

Histologic Grading of Gallbladder Carcinomas: This is an example of poorly-differentiated adenocarcinoma (< 50% glandular differentiation). The image shows small glands with poorly-formed or abortive lumens, cell nests, and single tumor cells infiltrating smooth muscle. For an example of well-differentiated tumor, see images 28-31.