Image Description
In multivariate analysis, proliferative activity as measured by MIB1 score has been shown to have independent prognostic value. Higher scores are linked with adverse outcome. In this case, Ki-67 appears to be positive in almost 70% of the nuclei (by visual estimation), consistent with rapid tumor growth. Courtesy of: Dr. Luciano de Souza Queiroz, Dept. of Pathology, Faculty of Medical Sciences, State University of Campinas (UNICAMP), Campinas, São Paulo State, BRAZIL. Additional images are here.