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Warthin's Tumor : Histochemistry

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This low power micrograph shows Warthin’s Tumor composed of papillary and tubular structures lined by bi-layered oncocytic epithelium and the dense lymphocytic infiltrate with prominent germinal center formation. The eosinophilic granular appearance of the cytoplasm of oncocytic cells is due to abundant mitochondria which can be demonstrated by phosohotungstic acid-hematoxylin stain (PTAH stain; appear as blue-black cytoplasmic granules).

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