LCH of Skin : Treatment
Treatment of Langerhans Cell Histiocytosis (LCH) of Skin: Solitary skin lesions in single system LCH can be treated by limited local excision. Weekly oral methotrexate with or without 6-mercaptopurine has also proven effective. Isolated skin lesions may also respond to light therapy. This image of LCH of skin shows a uniform population of Langerhans cells (LC) filling up the papillary dermis with some invading the epidermis. The LCs have characteristic folded or grooved nuclei.