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Solitary Fibrous Tumor of Bladder

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Solitary fibrous tumors (SFTs) can involve the urinary bladder. They may be discovered incidentally or present with hematuria and urinary obstruction. This low power view shows a spindle cell proliferation in a dense collagenous stroma. Given their rarity, SFTs are often mistaken for sarcomatoid carcinoma or sarcomas. Immunoreactivity for CD34 and bcl-2 and lack of staining with cytokeratins, EMA, and smooth muscle markers is diagnostic.

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