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Anaplastic Medulloblastoma

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Another example of large cell anaplastic medulloblastoma composed of sheets of highly atypical cells. A focus of necrosis is present just above the center of the image. The tumor cells have irregular hyperchromatic nuclei with nuclear molding and little cytoplasm. The age at presentation is younger than that for classic medulloblastomas. Most cases involve cerebellar vermis are and highly aggressive.

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