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Pindborg Tumor : Microscopic

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Calcifying epithelial odontogenic tumors usually show large areas of amorphous, eosinophilic, hyalinized extracellular amyloid or amyloid-like material (as seen here). Calcifications develop within these amyloid-like areas and form concentric rings known as Liesegang rings.

Some cases are hypercellular with minimal amyloid-like deposits and may even lack calcifications altogether. Others show only small nests and strands of epithelial cells engulfed by large diffuse areas of amyloid. A clear cell variant with cystic growth pattern has also been described.

Image courtesy of: Bin Xu, MD, PhD, Dept. of Pathology, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.

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