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Papillary Cystadenoma

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The epithelial cells are positive for pankeratin, cytokeratin 7, EMA (luminally accentuated; shown here), CEA, carbonic anhydrase IX, and vimentin. The tumor has some resemblance to clear cell papillary renal cell carcinoma, however, it is negative for CD10, RCC & AMACR.

Ref: Cox R, Vang R, Epstein J; Papillary Cystadenoma of the Epididymis and Broad Ligament : Morphologic and Immunohistochemical Overlap with Clear Cell Papillary Renal Cell Carcinoma. Am J Surg Pathol 2014;38:713-718. Image copyright: pathorama.ch

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