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LCH of Spleen

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Spleen is involved in about 13% of multifocal multisystem Langerhans cell histiocytosis (LCH). Rare cases of isolated splenic LCH have been reported. Spleen is considered a high-risk site. There is nodular involvement of the red pulp (as seen in this low magnification view) which may spill over secondarily into the white pulp.

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