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High-grade Papillary Urothelial Carcinoma (WHO/ISUP Classification, 2004) with Vascular Invasion

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Comments:
The tumor cell clusters conform to the shape of the vessel. Immunostain for CD31 confirmed the presence of an endothelial lining around the space. Vascular invasion should be distinguished from shrinkage artifact which would have no endothelial lining, blood, or lymphocytes.

slide 23 of 27