Plasmablastic lymphoma is an aggressive B-cell lymphoma seen in HIV+ individuals. The patient was a 42 y/o male who presented with aches and pain in the groin region. Work-up revealed a 10 cm. pelvic mass abutting the prostate and colon. Transrectal ultrasound-guided needle biopsies showed diffuse sheets of high-grade tumor cells with prominent nucleoli and scant to moderate cytoplasm.
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