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Lobular Carcinoma-In-Situ

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Comments:
The lobules are expanded and completely filled by a uniform population of round, small to medium-sized tumor cells. However, lobular enlargement and the complete absence of lumens are not absolute diagnostic requirements. Atypia, nuclear pleomorphism, mitotic activity and necrosis are usually absent except in a small subset of cases called Pleomorphic LCIS.

slide 4 of 20