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Cholesterol Gallstones : Pathophysiology Summary

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GallBladder_Cholelithiasis64_resized.jpg

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Pathophysiology of Cholesterol Gallstones - Summary: The formation of cholesterol gallstones is promoted by the following conditions:

  • supersaturation of bile with cholesterol
  • hypomotility of the gallbladder with bile stasis
  • cholesterol crystal nucleation
  • hypersecretion of gallbladder mucins that promote nucleation
The image shows mixed cholesterol stones containing cholesterol monohydrate and bilirubin calcium salts.

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