Facebook Icon Twitter icon Instagram icon Feedback

Acinic Cell Carcinoma : Differential

prev slide 50 of 143 next
No Image


The differential diagnosis includes Mammary analogue secretory carcinoma (MASC) which has several overlapping histologic features with acinic cell carcinoma. Features supporting MASC include: absence of basophilic zymogen granules in the cytoplasm, presence of strong immunoreactivity for mammaglobin and S-100 protein, and the presence of t(12;15)(p13;q25) translocation resulting in ETV6-NTRK-3 gene fusion. The image shows acinar cells arranged in a microcystic pattern.

prev slide 50 of 143 next