Image Description
References:
1. Goldblum, J. R., Weiss, S. W., & Folpe, A. L. (2020). Enzinger & Weiss's Soft Tissue Tumors - 7th Edition. Philadelphia, PA. Elsevier.
2. Soft Tissue and Bone Tumours. WHO Classification of Tumours (WHO Fascicle). 5th Edition 2020.
3. Goldblum, J. R. et al (2018). Rosai and Ackerman's Surgical Pathology - 11th Edition. Philadelphia, PA. Elsevier.
4. Calonje, E et al (2020). McKee's Pathology of the Skin with Clinical Correlations - 5th Ed. Elsevier.
This image of a hibernoma shows an admixture of: 1) large polygonal, round or ovoid cells with abundant granular eosinophilic cytoplasm, distinct cytoplasmic borders, and round centrally-placed nuclei; 2) multivacuolated large adipocytes with central nuclei; and 3) mature univacuolated adipocytes (white fat). There is no cytologic atypia and mitotic activity is not increased.
1. Goldblum, J. R., Weiss, S. W., & Folpe, A. L. (2020). Enzinger & Weiss's Soft Tissue Tumors - 7th Edition. Philadelphia, PA. Elsevier.
2. Soft Tissue and Bone Tumours. WHO Classification of Tumours (WHO Fascicle). 5th Edition 2020.
3. Goldblum, J. R. et al (2018). Rosai and Ackerman's Surgical Pathology - 11th Edition. Philadelphia, PA. Elsevier.
4. Calonje, E et al (2020). McKee's Pathology of the Skin with Clinical Correlations - 5th Ed. Elsevier.
This image of a hibernoma shows an admixture of: 1) large polygonal, round or ovoid cells with abundant granular eosinophilic cytoplasm, distinct cytoplasmic borders, and round centrally-placed nuclei; 2) multivacuolated large adipocytes with central nuclei; and 3) mature univacuolated adipocytes (white fat). There is no cytologic atypia and mitotic activity is not increased.