Nodular Fasciitis : Microscopic
Image Description
The lesional cells of nodular fasciitis are uniform, plump, immature-appearing fibroblasts and myofibroblasts resembling those seen in tissue culture. They are arranged in short, intersecting fascicles with a storiform growth pattern. The cells have oval, uniform nuclei with prominent nucleoli. Mitotic activity is brisk (1-2 mitoses/5HPF), but there are no atypical forms.
Scattered lymphocytes, extravasated red blood cells (and microhemorrhages), foamy histiocytes, and multinucleated giant cells are also present.
Scattered lymphocytes, extravasated red blood cells (and microhemorrhages), foamy histiocytes, and multinucleated giant cells are also present.