Sclerosing Epithelioid Fibrosarcoma
Image Description
High power view of sclerosing epithelioid fibrosarcoma (SEF) showing resemblance to carcinoma. Studies have shown the same translocation in SEF that was previously detected in 95% of low-grade fibromyxoid sarcomas (LGFMS): t(7;16) resulting in fusion of FUS gene to CREB3L2 gene suggesting that they are related - with LGFMS and SEF representing the low-grade end and high-grade end respectively of the same disease spectrum.