Giant Cell Tumor of Bone

Another example of giant cell tumor with classic histology. Treatment of giant cell tumors is usually curettage followed by filling the defect with bone chips. For destructive lesions, total resection or even amputation may be required. Recurrences occur in about 20% cases, sometimes after many decades. Malignant transformation (to osteosarcoma or fibrosarcoma) and metastases to lungs are other rare complications.