Dedifferentiated Chordoma : Brachyury
Image Description
By immunohistochemistry, there is positivity for both brachyury (shown here) and cytokeratin in the conventional component (seen here on the left) whereas the dedifferentiated areas are negative for brachyury (as seen here) and cytokeratin.
Image courtesy of: John Gross, MD; used with permission.
Image courtesy of: John Gross, MD; used with permission.