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Image Description

Lymph Node in Systemic Mastocytosis (SM): The diagnostic finding is presence of compact paracortical MC infiltrates. In some cases, the MC infiltrates are predominantly intrasinusoidal.

Additional findings include: Eosinophilic infiltrates (even eosinophilic microabscess in some cases), vascular proliferation, extramedullary hematopoiesis, and reticulin or collagen fibrosis.

Image 58 of 64