Image Description
Treatment of Langerhans Cell Histiocytosis (LCH) of Skin: Solitary skin lesions in single system LCH can be treated by limited local excision. Weekly oral methotrexate with or without 6-mercaptopurine has also proven effective. Isolated skin lesions may also respond to light therapy.
This image of LCH of skin shows a uniform population of Langerhans cells (LC) filling up the papillary dermis with some invading the epidermis. The LCs have characteristic folded or grooved nuclei.
This image of LCH of skin shows a uniform population of Langerhans cells (LC) filling up the papillary dermis with some invading the epidermis. The LCs have characteristic folded or grooved nuclei.