Image Description
Gross Pathology of Follicular Dendritic Cell Sarcoma (FDCS): The size ranges from 1 cm (usually involving cervical lymph nodes) to as much as 15-20 cm (involving retroperitoneum or mediastinum). The median size is about 5 cm. Tumor is well-circumscribed with a solid, pink-tan and homogenous surface. Areas of hemorrhage or necrosis may be present in larger tumors.
This image shows FDCS arising in colon. There is proliferation of a uniform population of spindle cells in fascicular, storiform, and whorled patterns. The spindle cells are admixed with an inflammatory infiltrate of small lymphocytes and plasma cells.
This image shows FDCS arising in colon. There is proliferation of a uniform population of spindle cells in fascicular, storiform, and whorled patterns. The spindle cells are admixed with an inflammatory infiltrate of small lymphocytes and plasma cells.