Myeloid Sarcoma : Ovary
Image Description
Myeloid sarcoma of the gynecologic tract is rare. The most commonly involved site is the uterus. Rare cases have been reported in the ovaries (shown here), fallopian tube, cervix, and vulva/vagina.
The histologic features are similar to those described previously in other locations. Primitive cells with varying degrees of maturation are arranged in diffuse sheets or infiltrating in single files through the ovarian stroma. The presence of eosinophilic myelocytes (cells with orange/red cytoplasm) in this case was a helpful diagnostic clue. The differential diagnostic considerations as well as immunophenotypic findings are similar to those seen in other sites.
The histologic features are similar to those described previously in other locations. Primitive cells with varying degrees of maturation are arranged in diffuse sheets or infiltrating in single files through the ovarian stroma. The presence of eosinophilic myelocytes (cells with orange/red cytoplasm) in this case was a helpful diagnostic clue. The differential diagnostic considerations as well as immunophenotypic findings are similar to those seen in other sites.