Image Description
Immunohistochemistry of Myeloid Sarcomas: The most common positive markers in paraffin sections include: CD68/KP1, MPO, CD117, CD99, lysozyme, CD34, TdT, CD43, CD56, CD61, CD163 (monocyte-specific), glycophorin and CD4.
Rare cases show aberrant expression of CD30 or cytokeratin.
T- and B-cell markers such as CD3, CD5, and CD20 are usually negative, although aberrant expression may be seen.
This image shows CD43 immunoreactivity in a case of megakaryoblastic myeloid sarcoma involving small bowel.
Image courtesy of: The New York Pathological Society (@NYPathSociety); used with permission.
Rare cases show aberrant expression of CD30 or cytokeratin.
T- and B-cell markers such as CD3, CD5, and CD20 are usually negative, although aberrant expression may be seen.
This image shows CD43 immunoreactivity in a case of megakaryoblastic myeloid sarcoma involving small bowel.
Image courtesy of: The New York Pathological Society (@NYPathSociety); used with permission.