Image Description
Pulmonary MALT Lymphoma - Morphology (continued): Pulmonary MALT lymphomas commonly infiltrate visceral pleura and form dense plaque-like areas. Areas of amyloid deposition or crystal-storing histiocytosis (due to intracytoplasmic crystalline immunoglobulin) may be present (see this image). Necrosis is uncommon in MALT lymphomas and its presence may signal transformation to DLBCL. Plasmacytic differentiation may be so prominent that a diagnosis of plasmacytoma may be entertained on transbronchial biopsies. Dutcher bodies may be seen in cases with plasmacytic differentiation.
This image shows neoplastic centrocyte-like cells engulfing and invading a residual germinal center.
This image shows neoplastic centrocyte-like cells engulfing and invading a residual germinal center.