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The predominant lesional cells in Kikuchi lymphadenitis are histiocytes, plasmacytoid dendritic cells, and activated T-cells.
Histiocytes often show crescentic nuclei and contain phagocytized debris (as seen here). They are CD68+, CD163+, and contain cytoplasmic myeloperoxidase.
The plasmacytoid dendritic cells are CD123+ and TCL1+ and cluster at the periphery of necrotic lesions.
Histiocytes often show crescentic nuclei and contain phagocytized debris (as seen here). They are CD68+, CD163+, and contain cytoplasmic myeloperoxidase.
The plasmacytoid dendritic cells are CD123+ and TCL1+ and cluster at the periphery of necrotic lesions.