Salivary Duct Carcinoma : GCDFP-15

Immunohistochemical Profile of Salivary Duct Carcinomas: Salivary duct carcinomas are positive for CK7, EMA, CEA, and GATA-3 (nuclear staining). GCDFP-15 (shown here) is focally positive. They are also HER-2, EGFR, and androgen receptor positive while ER and PR are negative. The Ki-67 proliferation index is usually high.

Image courtesy of: @PatholWalker