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Treatment & Prognosis: All types of ovarian fibromas (conventional, mitotically-active, cellular) pursue a benign course and have an excellent prognosis. Conservative surgical treatment consisting of unilateral oophorectomy is sufficient. Any associated ascites or pleural effusion rapidly resolves following surgery.
A small percentage of cases, usually cellular fibromas, are associated with ovarian surface rupture resulting in extraovarian adhesions and peritoneal implants. As long as both the tumor and the implants appear histologically benign, this is not considered a sign of malignancy and the prognosis remains excellent. Such cases, however, require long-term follow-up due to the possibility of local recurrence, which is usually delayed by several years.
This image of an ovarian fibroma shows fascicles of bland, fibroblast-type spindle cells and dense hyaline plaques in the stroma.
A small percentage of cases, usually cellular fibromas, are associated with ovarian surface rupture resulting in extraovarian adhesions and peritoneal implants. As long as both the tumor and the implants appear histologically benign, this is not considered a sign of malignancy and the prognosis remains excellent. Such cases, however, require long-term follow-up due to the possibility of local recurrence, which is usually delayed by several years.
This image of an ovarian fibroma shows fascicles of bland, fibroblast-type spindle cells and dense hyaline plaques in the stroma.