Immature Teratoma : Treatment
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TREATMENT: The treatment of high-grade (grades II and III) immature ovarian teratomas is surgery followed by combination chemotherapy. The 5-yr survival rate for Stage I tumors is almost 100%.
Grade and stage of the primary tumor and grade of the metastasis are the main prognostic factors. After treatment, if the metastatic deposits contain only mature tissues, it is a good prognostic sign. If the extraovarian deposits of mature teratomatous tissues develop after chemotherapy, it is referred to as growing teratoma syndrome - a finding more frequently associated with testicular germ cell tumors.
About this image: Immature ovarian teratoma with a focus of mature somatic tissues. On the lower right are intestinal-type glands; seromucinous salivary-type acini are on the upper left; a nerve is seen diagonally from lower left to upper right; and clusters of neurons are seen on the lower left corner.
Grade and stage of the primary tumor and grade of the metastasis are the main prognostic factors. After treatment, if the metastatic deposits contain only mature tissues, it is a good prognostic sign. If the extraovarian deposits of mature teratomatous tissues develop after chemotherapy, it is referred to as growing teratoma syndrome - a finding more frequently associated with testicular germ cell tumors.
About this image: Immature ovarian teratoma with a focus of mature somatic tissues. On the lower right are intestinal-type glands; seromucinous salivary-type acini are on the upper left; a nerve is seen diagonally from lower left to upper right; and clusters of neurons are seen on the lower left corner.