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TREATMENT: The treatment of high-grade (grades II and III) immature ovarian teratomas is surgery followed by combination chemotherapy. The 5-yr survival rate for Stage I tumors is almost 100%.

Grade and stage of the primary tumor and grade of the metastasis are the main prognostic factors. After treatment, if the metastatic deposits contain only mature tissues, it is a good prognostic sign. If the extraovarian deposits of mature teratomatous tissues develop after chemotherapy, it is referred to as growing teratoma syndrome - a finding more frequently associated with testicular germ cell tumors.

About this image: Immature ovarian teratoma with a focus of mature somatic tissues. On the lower right are intestinal-type glands; seromucinous salivary-type acini are on the upper left; a nerve is seen diagonally from lower left to upper right; and clusters of neurons are seen on the lower left corner.

Image 75 of 183