Urothelial Carcinoma-In-Situ : Pagetoid Spread
Section Editor: Dharam M. Ramnani, MD
Virginia Urology, Richmond, VA, USA
Image Description
Urothelial CIS may spread into the adjacent normal urothelium in a pagetoid fashion. Several individual tumor cells with features of CIS are present within the normal urothelium. The tumor cells have voluminous eosinophilic cytoplasm and enlarged hyperchromatic nuclei.