Urothelial Carcinoma with Squamous Differentiation
Section Editor: Dharam M. Ramnani, MD
Virginia Urology, Richmond, VA, USA
Image Description
The presence of keratin pearls and copious keratin production is unequivocal for squamous differentiation in this urothelial carcinoma. Such foci comprised approximately 5% of the tumor. The presence of focal squamous differentiation in a urothelial carcinoma does not appear to have any prognostic significance.