Urothelial Carcinoma - Nested Variant

The nested variant of urothelial carcinoma consists of small, discrete nests with bland morphology distributed irregularly in the lamina propria. The overlying urothelium is usually unremarkable. In the deeper aspects of the tumor, the nests may anastomose or become confluent and exhibit greater cytolgic atypia. The size of nests is much smaller than von Brunn's nests of normal urothelium.