Myxoid Leiomyosarcoma
Section Editor: Dharam M. Ramnani, MD
Virginia Urology, Richmond, VA, USA
Image Description
Leiomyosarcoma is the most common malignant soft tissue tumor arising in the bladder of adults. The age at presentation is usually between 60 and 75 yrs. with a slight male predilection. Exposure to cyclophosphamide therapy is a risk factor. This low power view shows a spindle cell proliferation with abundant myxoid stroma underneath an intact urothelial lining.