Testis : CLL & DLBCL
Section Editor: Dharam M. Ramnani, MD
Virginia Urology, Richmond, VA, USA
Image Description
Large B-cell Lymphoma of the Testis in a background of CLL/SLL (same case as the previous four images): This field shows predominantly large atypical lymphoid cells with vesicular nuclei and prominent nucleoli. They had the following immunophenotype: CD19+, CD20 mod+, CD5-, CD23-, CD10+, and kappa mod+. This may be a composite lymphoma (a CD10+ large B-cell lymphoma along with a co-existing CLL/SLL) OR a progression/transformation of CLL/SLL.