Section Editor: Dharam M. Ramnani, MD

Virginia Urology, Richmond, VA, USA

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Testicular Lymphoma - Clinical Features: The mean age at presentation is late 50's or 60's. They are rare in children. Patients present with a unilateral, slowly-enlarging, hard, painless scrotal mass. There is bilateral involvement in 10-15% of cases. Lymphomas are the most frequent bilateral tumor of the testis. Constitutional symptoms are seen in a minority of patients.

At presentation, 50% of patients have Ann Arbor Stage I disease, 25% have Stage II, and 25% have Stage IV disease. Patients with advanced stage may have symptoms related to involvement of CNS, bone, bone marrow, skin, orbit, and other locations.

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