Embryonal CA : CD30 Immunostain
Section Editor: Dharam M. Ramnani, MD
Virginia Urology, Richmond, VA, USA
Image Description
CD30 immunoreactivity (shown here) is seen in almost 85% of cases of embryonal carcinoma and is a useful diagnostic marker. The immunohistochemical profile of embryonal carcinoma is as follows: cytokeratin +, PLAP +, OCT3/4 +, CD30 +, EMA -ve, and c-kit-ve. When evaluating CD30 positivity in a poorly-differentiated neoplasm, one should keep in mind that anaplastic large cell lymphomas are also CD30 positive.