HMWCK in Adenosis
Section Editor: Dharam M. Ramnani, MD
Virginia Urology, Richmond, VA, USA
Image Description
With high molecular weight cytokeratin immunostain, fragmented basal cell layer is seen in at least 50% of the glands. In lesions suspected of being adenosis, the absence of basal cell staining in a few glands should not be used as evidence of cancer, as long as these glands resemble their neighbors with patchy basal cell staining.