Section Editor: Dharam M. Ramnani, MD

Virginia Urology, Richmond, VA, USA

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Image Description

Immunohistochemical markers for basal cells are useful in confirming the diagnosis of atypical adenomatous hyperplasia (adenosis) in prostate needle biopsies. The basal cell layer is fragmented but present in at least some of the acini within the focus. Since the glands lacking basal cells are morphologically similar to those with patchy staining, the entire focus is considered benign.

Image 5 of 19