Section Editor: Dharam M. Ramnani, MD

Virginia Urology, Richmond, VA, USA

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Introduction: Renal dysplasia is the most common form of cystic renal disorder in children and a frequent cause of abdominal masses in the newborn. It is a consequence of anomalous development of the metanephros. The word dysplasia refers to renal maldevelopment and does not imply predisposition to neoplasia.

This autopsy specimen of urinary system from a neonate shows bilateral multicystic renal dysplasia and bilateral hydronephrosis secondary to obstruction of uretero-pelvic junction. Both kidneys are replaced by misshapen masses of variably-sized, thin-walled cysts. See close up in the next image.

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