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The cysts in multilocular cystic renal neoplasm of low malignant potential are lined by a single layer of small bland clear cells without nucleoli, typical of WHO/ISUP Grade grade 1 or 2 nuclei.
The presence of grade 3 or 4 nuclei, expansile nodules of tumor cells, necrosis, or sarcomatous change is incompatible with the diagnosis of multilocular cystic renal neoplasm of LMP.
The presence of grade 3 or 4 nuclei, expansile nodules of tumor cells, necrosis, or sarcomatous change is incompatible with the diagnosis of multilocular cystic renal neoplasm of LMP.